Firstly the shot is used to start [Ozymandias] in the flashback when Skyler is packing away the clown she sold.
The shot itself holds so much meaning because of the phone placed right next to the knives. It shows how much different Skyler is and how strong she’s become. Instead of calling for help (reaching for the phone) she reaches for a knife to defend herself and her family from the monster Walt has become.
Interestingly enough, the knife she grabs is the same knife Walt puts away in Season 2, Episode 1 “Seven Thirty-Seven”. [x]
"[Renee] cheerfully accepted the Herculean task and worked without adequate rest or food […] changed dressings, fed patients unable to feed themselves, gave out medications, bathed and made the patients more comfortable […] her very presence among those wounded men seem to be an inspiration to those whose morale had declined from prolonged suffering.”
What piqued Miller’s interest was how “understanding” and “helpful” Sherlock was, traits the actor believes were rarely communicated. “In the books, I found him to be a much more understanding guy. I feel that he really likes people a little bit more than I had seen recently — not that he can necessarily communicate that very well. He likes the underdog, and he likes people who are downtrodden, who are having a hard time. He generally wants to help. I found him to be a much more helpful person, so I tried to put a bit of that in, even though he doesn’t quite pull it off.”[x]